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Evista No Prescription
Evista is prescribed to treat and prevent osteoporosis, the brittle-bone disease that strikes some women after menopause.
A variety of factors promote osteoporosis. The more factors that apply to you, the greater your chances of developing the
disease. These factors include:
- A diet low in calcium;
- An inactive lifestyle;
- Caucasian or Asian descent;
- Early menopause;
- Most important fact about Evista;
- Osteoporosis in the family;
- Slender build;
Like estrogen, Evista reduces bone loss and increases bone density. However, Evista does not have estrogen-like effects on
the uterus and breasts, and therefore is unlikely to increase the risk of cancer, as estrogen therapy sometimes can do.
Although Evista has been shown to increase bone density over the course of a two-year study, its longer-term ability to
prevent bone fractures has not yet been proven.
Evista tablets contain the active ingredient raloxifene hydrochloride, which is a type of drug called a selective
oestrogen receptor modulator.
Oestrogen, the main female sex hormone, has many actions throughout the body. Bone tissue, cholesterol metabolism, breast
tissue and uterine tissue are all affected by this hormone. At the menopause, blood levels of oestrogen start to decrease and
this affects the tissues that are normally responsive to oestrogen.
In terms of bone tissue, declining levels of oestrogen result in an increase in bone breakdown, which can lead to a loss
of bone density. Bone loss is particularly rapid for the first ten years after the menopause and it may lead to the
development of osteoporosis - a condition in which the bones are weak and break more easily.
Raloxifene is prescribed to both prevent and treat osteoporosis in postmenopausal women. It works by acting on oestrogen
receptors in the bone tissue, where it mimicks the natural effects of oestrogen. This gradually reverses the excessive
breakdown of bone that happens at menopause and causes an increase in bone mineral density, making bones stronger. Raloxifene
has been shown to significantly reduce the risk of spinal fractures, but not hip fractures.
Raloxifene selectively mimicks the effects of oestrogen on bone tissue, but does not affect breast tissue or uterine
tissue. This means that long-term use does not carry the increased risk of cancer of the lining of the womb or breast cancer
that is associated with long-term use of oestrogen-based hormone replacement therapy. However, raloxifene is associated with
an increased risk of developing blood clots in the veins. This risk is similar to that associated with hormone replacement
Due to its selective activity, raloxifene is not effective at relieving other symptoms of oestrogen deficiency that occur
during the menopause, for example hot flushes.
Why is Evista bought?
- Prevention and treatment of osteoporosis in women who have passed the menopause.
Evista Side Effects
Evista side effects that you should report to your health care professional or doctor as soon as possible:
- weight gain;
- uterine discharge;
- urinary tract infection;
- tendon soreness;
- stomach and intestinal problems;
- sore throat;
- nasal inflammation;
- muscle ache;
- leg cramps;
- joint pain;
- increased cough;
- hot flashes;
- gynecological problems;
- flu symptoms;
- chest pain;
- breast pain;
- swelling of the legs and ankles due to excess fluid retention;
- rise in blood pressure;
- nausea and vomiting;
- leg cramps;
- hot flushes;
- flu-like symptoms;
- decreased numbers of platelets in the blood;
- breast pain englargement or tenderness;
- blood clots in the veins;
- blood clot in an artery;
- abdominal pain;
The recommended dosage is one 60-mg tablet once a day.