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Eldepryl No Prescription
Eldepryl tablets and syrup contain the active ingredient Eldepryl hydrochloride, which is a type of drug called a
selective monoamine-oxidase-B inhibitor. Eldepryl is available without a brand name, ie as the generic drug. Eldepryl
increases the levels of a substance in the brain called dopamine, and is prescribed in the treatment of Parkinson's disease.
Dopamine is a substance known as a neurotransmitter. Neurotransmitters are present in the brain and nervous system and
are involved in transmitting messages between nerves. These messages allow the normal functioning of the body. The
neurotransmitter dopamine is known to be reduced or absent in the brains of people with Parkinson's disease, and this is
thought to be the cause of the disease symptoms. The mainstay of treating Parkinson's disease is to replace dopamine in the
Natural dopamine released from nerve cells in the brain is normally broken down by an enzyme called monoamine-oxidase-B.
Eldepryl works by blocking the action of this enzyme, which prevents the monoamine-oxidase-B from breaking down the dopamine.
This results in an increased amount of active dopamine in the brain, and this reduces the symptoms of Parkinson's disease.
Eldepryl is usually prescribed in combination with a drug called levodopa to treat Parkinson's disease. Levodopa is
converted into dopamine in the brain and therefore works by directly replacing the lost dopamine. Unfortunately, levodopa
treatment tends to become less effective over time and patients tend to experience 'end-of-dose' deterioration, where the
duration of benefit after each dose of levodopa becomes progressively shorter. Eldepryl can be prescribed to prolong the
effect of levodopa, because it stops the dopamine that is formed from the levodopa from being broken down in the brain.
This extends the action of levodopa thereby reducing the 'end-of-dose' side effects.
Why is Eldepryl bought?
- Parkinson's disease;
Eldepryl is prescribed along with Sinemet for people with Parkinson's disease. Eldepryl is prescribed
when Sinemet no longer seems to be working well. Eldepryl has no effect when taken by itself; it works only in combination
with Larodopa or Sinemet.
Parkinson's disease, which causes muscle rigidity and difficulty with walking and talking, involves the progressive
degeneration of a particular type of nerve cell. Early on, Larodopa or Sinemet alone may alleviate the symptoms of the
disease. In time, however, these drugs work less well; their effectiveness seems to switch on and off at random, and the
individual may begin to experience side effects such as involuntary movements and "freezing" in mid-motion.
Eldepryl may be prescribed at this stage of the disease to help restore the effectiveness of Larodopa or Sinemet.
When you begin to take Eldepryl, you may need a reduced dosage of the other drug.
Eldepryl Side Effects
Eldepryl side effects that you should report to your health care professional or doctor as soon as possible:
- dry mouth;
- skin reactions such as rash and itch;
- nausea and vomiting;
- mouth ulcers;
- dry mouth;
- disturbed sleep;
- difficulty in passing urine;
- balance problems involving the inner ear;
- alteration in results of liver function tests;
- a drop in blood pressure that occurs when going from lying down to sitting or standing which results in dizziness and lightheadedness;
- abdominal pain;
The recommended dose of Eldepryl is 10 mg per day divided into 2 smaller doses of 5 mg each, taken at breakfast and lunch. There is no evidence of additional benefit from higher doses, and they increase the risk of side effects.
The use of Eldepryl in children has not been evaluated.